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Hydroxypropyl-Beta-Cyclodextrin
Feature:
Hydroxypropyl beta-cyclodextrin are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.
CAS No.: 128446-35-5
Molecular Formula: C63H112O42
Molecular Weight: 1541.54
Specifications：
1. Appearance: White powder
2. Assay: ≥98%
3. Loss on Drying: ≤4.5%
4. Chloride: ≤0.02%
5. Residue on Ignition: ≤1.5%
6. Heavy Metals: ≤0.0025%
7. As: ≤0.0002%
8. Degree of substitution: 4-9
9. Total bacteria count: ≤1000 pcs/g
10. Moulds and yeasts: ≤100 pcs/g
Application:
Pharmaceutical:
1. Suitable for parenteral use, syrups, solutions and oral suspensions as well as for dry formulations (with possibility of in-situ encapsulation).
2. To increase water solubility of poorly soluble drugs.
3. To increase bioavailability.
4. To improve organoleptic properties of bitter or unpleasant actives.
Cosmetics:
1. Suitable for encapsulation of volatile compounds.
2. To increase shelf life of expensive flavours.
