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【The different name 】 soil acid Oleanol, angelica Caryophyllia, Astrantigeninc, Giganteumgeninc
【 EINECS th 】 208-081-6 [1]
【 to source 】 the main source MuXi secco plant extract neat trick fruit olea europaea l. leaves; Privet ligustrum lucidum ait.
【 points son type 】 C30H48O3
【 points son quantity 】 456.71
【 composition classification 】 triterpene rings
【 rules case 】 98%
【 pharmacological effect 】
1. Reduce liver damage: oleanolic acid for five rings triterpene compound to caused by carbon tetrachloride rat acute or chronic liver damage have obvious protection. After the treatment, swollen mitochondria and expansion of the rough endoplasmic reticulum restoration. Still can make the acute and chronic liver damage the liver cell balloon sample degeneration and necrosis and significantly reduce the inflammatory response. Intrahepatic triglyceride accumulation reduce, sugar the original estimates increase.
2. The lowering of plasma cereal third transaminase activity: oleanolic acid of acute and chronic hepatitis and cirrhosis animals are obviously drop enzyme action.
3. Reduce serum r-globulin, and histological observation and see the liver inflammation reduce are in agreement.
4. Promoting liver cells regeneration, oleanolic acid can make rat liver nuclear division of residual significantly increased in number, renewable degrees higher than those in the control group, the tip has promote cell regeneration role.
5. Reduce cirrhosis rats homogenate cool acid level: by a brain homogenate cool acid level declined obviously, can restrain mimicked the neurotransmitter generation, it is beneficial to the prevention and control of the hepatic encephalopathy.
6. The liver fiber hyperplasia: via oleanolic acid treatment of hepatic fibrosis rats, liver fiber hyperplasia seriously and significantly reduce, liver collagen protein content decrease, tip has the function of prevention and control of liver cirrhosis.
7. Oleanolic acid mononuclear cells in mice engulfed system, the function of macrophage cell and experimental arthritis had significant inhibitory effect, but to the opposite sex humoral immune function and the antigen cells have influence. Enhance immune and inhibition of S180 plant.
8. Damage to chromosome has protective effect, on experimental atherosclerosis prevention effect, still can correct protein metabolization obstacle.
